Toxic epidermal necrosishttps://en.wikipedia.org/wiki/Toxic_epidermal_necrolysis
Toxic epidermal necrosis jẹ iru iṣesi awọ ara ti o lagbara. Awọn aami aisan ibẹrẹ pẹlu iba ati awọn aami aisan-aisan. Awọn ọjọ diẹ lẹhinna awọ ara bẹrẹ lati roro ati peeli ti o n dagba awọn agbegbe ti o ni irora. O ṣe pataki ki awọn membran mucous, gẹgẹbi ẹnu, tun jẹ deede. Awọn ilolu pẹlu gbigbẹ gbigbẹ, sepsis, pneumonia, ati ikuna awọn ara eniyan pupọ.

Idi ti o wọpọ julọ jẹ awọn oogun kan gẹgẹbi lamotrigine, carbamazepine, allopurinol, sulfonamide aporo, ati nevirapine. Awọn okunfa ewu pẹlu HIV ati lupus erythematosus eto-ara. Itọju maa n waye ni ile-iwosan gẹgẹbi ni ile-iṣẹ sisun tabi apakan itọju aladanla.

○ Itọju
Eyi jẹ aisan to ṣe pataki, nitorinaa ti o ba kan awọn ete tabi ẹnu rẹ tabi awọ ara rẹ di roro, wo dokita rẹ ni kete bi o ti ṣee.
Awọn oogun ifura yẹ ki o dawọ duro. (fun apẹẹrẹ, awọn egboogi, awọn oogun egboogi-iredodo ti kii ṣe sitẹriọdu)

☆ Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
  • Isonu awọ ara abuda ti Toxic epidermal necrosis
  • TENS ― ọjọ 10
  • Necrolysis epidermalis toxica
  • Awọn roro ni ibẹrẹ ipele le yara ni ilọsiwaju lati kan gbogbo ara laarin awọn ọjọ diẹ.
References Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management 34577817 
NIH
Stevens-Johnson Syndrome (SJS) ati Toxic Epidermal Necrolysis (TEN) jẹ awọn ipo toje nibiti awọ ara ti ni iriri negirosisi nla ati sisọ silẹ. Ni awọn ofin ti itọju, cyclosporine jẹ imunadoko pupọ fun SJS, lakoko ti idapọ ti immunoglobulin inu iṣọn-ẹjẹ (IVIg) ati awọn corticosteroids ṣiṣẹ dara julọ fun awọn ọran ti SJS ati TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
 Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches 36469487
Toxic epidermal necrolysis (TEN) jẹ ifarapa awọ ara to ṣe pataki ti o fa nipasẹ awọn oogun kan ati iṣẹ ṣiṣe eto ajẹsara, ti o fa iyọkuro iwọn nla ti awọ ara ita (epidermis) , ti o kan diẹ sii ju 30% ti dada ti ara. TEN ni oṣuwọn iku ti o ju 20% lọ, nigbagbogbo nitori awọn akoran ati awọn iṣoro mimi. Idaduro oogun ti o nfa iṣesi, pese itọju atilẹyin, ati lilo awọn itọju afikun le mu abajade dara si. Awọn ijinlẹ aipẹ ti fihan pe awọn oogun bii cyclosporine, tumor necrosis factor alpha inhibitors, ati apapo ti ajẹsara globulin ati awọn corticosteroids le ṣe iranlọwọ, ti o da lori awọn idanwo iṣakoso aileto ati awọn itupalẹ ti awọn iwadii pupọ.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
 Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review 32520664 
NIH
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.